Wednesday, April 9, 2014

Direct application of Cas9 protein + CRISPR RNA to cells

Here's the two recent papers in Genome Research describing transfer of Cas9 protein + guide RNA directly to cells, with efficiency and reduced off-target effects.

Ramakrishna S, Kwaku Dad AB, Beloor J, Gopalappa R, Lee SK, Kim H.
Genome Res. 2014 Apr 2. [Epub ahead of print]


Kim S, Kim D, Cho SW, Kim J, Kim JS.
Genome Res. 2014 Apr 2. [Epub ahead of print]

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